Models to Combat
Cancer & Aging
About us
a Dutch research institute

An excellent environment  to facilitate groundbreaking research

The Models to Combat Cancer (MCCA) is a Dutch research center for development and utilization of preclinical models in basic and translational cancer and aging-related research.
The MCCA is the Dutch partner in the European INFRAFRONTIER and EUROPDX infrastructures.
People behind the research & development

The MCCA team

Facility leaders
Key researchers
Scientific advisory board
All MCCA members
Prof. Dr. Floris Foijer
Prof. Dr. Floris Foijer
,
Genetics, mouse models, cancer Head of the iPSC/CRISPR facility
UMCG
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ORCID profile
Dr. Debby Koonen
Dr. Debby Koonen
,
Mouse models, cardio-vascular metabolism, microbiome, intervention models
UMCG
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ORCID profile
Dr. Marieke van de Ven
Dr. Marieke van de Ven
,
Head of animal facility, project management, study design and license preparation, interventions
Netherlands Cancer Institute
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ORCID profile
Prof.dr. Jos Jonkers
Prof.dr. Jos Jonkers
,
Genetics, Mouse models, DNA repair, breast cancer
Netherlands Cancer Institute
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ORCID profile
Dr. Jeroen Essers
Dr. Jeroen Essers
,
In vivo molecular imaging
Erasmus MC
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ORCID profile
Dr. Paul Krimpenfort
Dr. Paul Krimpenfort
Mouse Modelling, Head of Animal Model facility
Netherlands Cancer Institute
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ORCID profile
Prof.dr. Bart van de Sluis
Prof.dr. Bart van de Sluis
,
Aging, Genetics, Mouse Models, Dyslipidemia and liver disease
UMCG
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ORCID profile
Prof.dr. Roland Kanaar
Prof.dr. Roland Kanaar
,
Cancer, Molecular Biology, Genetics
Erasmus MC
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ORCID profile
Prof.dr. Rob Coppes
Prof.dr. Rob Coppes
,
Cancer, radiation biology, particle therapy
UMCG
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ORCID profile
Dr. Ingrid van der Pluijm
Dr. Ingrid van der Pluijm
,
Cardiovascular aging, aging mouse models, intervention studies
Erasmus MC
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ORCID profile
Prof.dr. Alain de Bruin
Prof.dr. Alain de Bruin
,
Anatomic and molecular pathology in cancer & aging
University of Utrecht
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ORCID profile
Dr. Jan Freark de Boer
Dr. Jan Freark de Boer
Bile acid and lipid metabolism
UMCG
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ORCID profile
Prof. Dr. Floris Foijer
Prof. Dr. Floris Foijer
,
Genetics, mouse models, cancer Head of the iPSC/CRISPR facility
UMCG
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ORCID profile
Dr. Bart Westendorp
Dr. Bart Westendorp
Cancer, Single cell seq and imaging, Bioinformatics
University of Utrecht
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ORCID profile
Prof. Dr. Sanne Schagen
Prof. Dr. Sanne Schagen
Cancer and cognition
Netherlands Cancer Institute
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ORCID profile
Dr. Ji Ying Song
Dr. Ji Ying Song
Comparative and experimental pathology
Netherlands Cancer Institute
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ORCID profile
Dr. Debby Koonen
Dr. Debby Koonen
,
Mouse models, cardio-vascular metabolism, microbiome, intervention models
UMCG
Profile page
ORCID profile
Prof.dr. Jos Jonkers
Prof.dr. Jos Jonkers
,
Genetics, Mouse models, DNA repair, breast cancer
Netherlands Cancer Institute
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ORCID profile
Prof.dr. Karin de Visser
Prof.dr. Karin de Visser
Tumor Biology, Immunology, Metastasis, Breast Cancer
Netherlands Cancer Institute
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ORCID profile
Dr. Leila Akkari
Dr. Leila Akkari
Tumor Biology, Immunology, TME, Cancer Treatment, Imaging
Netherlands Cancer Institute
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ORCID profile
Dr. Jeroen Essers
Dr. Jeroen Essers
,
In vivo molecular imaging
Erasmus MC
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ORCID profile
Prof.dr. Jan Hoeijmakers
Prof.dr. Jan Hoeijmakers
DNA damage repair, aging and cancer, mouse models, repair syndromes
Erasmus MC
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Dr. Dik van Gent
Dr. Dik van Gent
Cancer-on-chip, Cancer treatment response prediction
Erasmus MC
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Dr. Olaf van Tellingen
Dr. Olaf van Tellingen
Cancer, pharmacology, cognition Head of animal pharmacology unit
Netherlands Cancer Institute
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ORCID profile
Prof.dr. Bart van de Sluis
Prof.dr. Bart van de Sluis
,
Aging, Genetics, Mouse Models, Dyslipidemia and liver disease
UMCG
Profile page
ORCID profile
Prof.dr. Roland Kanaar
Prof.dr. Roland Kanaar
,
Cancer, Molecular Biology, Genetics
Erasmus MC
Profile page
ORCID profile
Prof.dr. Rob Coppes
Prof.dr. Rob Coppes
,
Cancer, radiation biology, particle therapy
UMCG
Profile page
ORCID profile
Dr. Ingrid van der Pluijm
Dr. Ingrid van der Pluijm
,
Cardiovascular aging, aging mouse models, intervention studies
Erasmus MC
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ORCID profile
Prof.dr. Hans Jonker
Prof.dr. Hans Jonker
Aging, Molecular genetics, Type 2 diabetes, Non-alcoholic fatty liver disease
UMCG
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ORCID profile
Dr. Richard Wubbolts
Dr. Richard Wubbolts
Cellular imaging & AI-based fluorescence quantification in cancer & aging
University of Utrecht
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Prof.dr. Alain de Bruin
Prof.dr. Alain de Bruin
,
Anatomic and molecular pathology in cancer & aging
University of Utrecht
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ORCID profile
Prof.dr. Jacco van Rheenen
Prof.dr. Jacco van Rheenen
Cancer, High resolution intra-vital microscopy
Netherlands Cancer Institute
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ORCID profile
Yann Herault
Yann Herault
Generation of GEMMs, metabolism, aging
IGBMC, Strasbourg, France
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Prof. Dr. Dr. h.c. Martin Hrabé de Angelis
Prof. Dr. Dr. h.c. Martin Hrabé de Angelis
Metabolism, German mouse clinic
HC Munich, Germany
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Prof. Dr. Med. Vet. Sven Rottenberg
Prof. Dr. Med. Vet. Sven Rottenberg
Veterinary pathology, cancer therapy resistance
University of Bern, Switzerland
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Prof. Dr. Mechthild Krause
Prof. Dr. Mechthild Krause
Particle therapy, nuclear imaging
HZDR, Germany
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Prof. Jean-Christophe Marine
Prof. Jean-Christophe Marine
Mouse models of human cancer
VIB, Belgium
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Yann Herault
Yann Herault
IGBMC, Strasbourg, France
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Prof. Dr. Dr. h.c. Martin Hrabé de Angelis
Prof. Dr. Dr. h.c. Martin Hrabé de Angelis
HC Munich, Germany
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Prof. Dr. Med. Vet. Sven Rottenberg
Prof. Dr. Med. Vet. Sven Rottenberg
University of Bern, Switzerland
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Prof. Dr. Mechthild Krause
Prof. Dr. Mechthild Krause
HZDR, Germany
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Prof. Jean-Christophe Marine
Prof. Jean-Christophe Marine
VIB, Belgium
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Dr. Jan Freark de Boer
Dr. Jan Freark de Boer
UMCG
Profile page
ORCID profile
Dr. Bart Westendorp
Dr. Bart Westendorp
University of Utrecht
Profile page
ORCID profile
Prof. Dr. Sanne Schagen
Prof. Dr. Sanne Schagen
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Ji Ying Song
Dr. Ji Ying Song
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Marieke van de Ven
Dr. Marieke van de Ven
,
Netherlands Cancer Institute
Profile page
ORCID profile
Prof.dr. Jos Jonkers
Prof.dr. Jos Jonkers
,
Netherlands Cancer Institute
Profile page
ORCID profile
Prof.dr. Karin de Visser
Prof.dr. Karin de Visser
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Leila Akkari
Dr. Leila Akkari
Netherlands Cancer Institute
Profile page
ORCID profile
Prof.dr. Jan Hoeijmakers
Prof.dr. Jan Hoeijmakers
Erasmus MC
Profile page
ORCID profile
Dr. Dik van Gent
Dr. Dik van Gent
Erasmus MC
Profile page
ORCID profile
Dr. Paul Krimpenfort
Dr. Paul Krimpenfort
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Olaf van Tellingen
Dr. Olaf van Tellingen
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Ingrid van der Pluijm
Dr. Ingrid van der Pluijm
,
Erasmus MC
Profile page
ORCID profile
Dr. Richard Wubbolts
Dr. Richard Wubbolts
University of Utrecht
Profile page
ORCID profile
Prof.dr. Alain de Bruin
Prof.dr. Alain de Bruin
,
University of Utrecht
Profile page
ORCID profile
Prof.dr. Jacco van Rheenen
Prof.dr. Jacco van Rheenen
Netherlands Cancer Institute
Profile page
ORCID profile
Dr. Shuraila Zerp
Dr. Shuraila Zerp
Netherlands Cancer Institute
Profile page
ORCID profile

Contact MCCA

For all general inquiries about MCCA, our facilities and services or how we can help with your research to combat cancer and aging, please contact Marieke van de Ven.
Marieke van de Ven
m.vd.ven@nki.nl
Netherlands Cancer Institute, Amsterdam, The Netherlands

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