With our innovative research and high-tech facilities we want to better understand the underlying biology that drives aging and cancer and help researchers with their research.
The goals of our consortium are
to further improve the detection, diagnosis and treatment of cancer & aging
to offer researchers the full compendium of model systems
to provide infrastructure for new and complementary technology platforms
Organoid of mouse intestine - Saskia Suijkerbuijk (NKI)
3 steps in preclinical research
How we can help researchers
Cancer intestinal organoid - Saskia Suijkerbuijk (NKI)
1
We help you choose the right model
Do you need a model for your research on aging & cancer? We can help find or develop the most appropriate one for your research question. Non-animal models where possible, animal models where needed.
2
We facilitate intervention studies
What intervention do you need to answer your research question and test your scientific hypothesis? We can help identify the right tools and technologies. Maybe it's a combination of therapeutics and disease models, or genetic modification.
3
We evaluate & improve
We help you determine the most advanced technologies to evaluate the effect of your intervention. We help choose the right pathological analysis and imaging methodology.
Our research facilities
Advanced facilities to improve your research
MCCA provides an accessible infrastructure of advanced facilities, that enables a comprehensive continuum of model system generation, innovative interventions and in-depth evaluation. The aim is to better understand the underlying biology and develop new therapies in cancer and aging.
facilities for developing animal & non-animal models
facilities for interventions in cancer & aging
facilities for evaluation with advanced imaging & pathology
A joint effort to facilitate groundbreaking research
With a rapidly aging population world-wide, cancer and other aging-related diseases are on the rise and therefore a major concern to society. In Models to Combat Cancer and Aging (MCCA), several Dutch research institutes join forces to facilitate groundbreaking research and accelerate cancer and aging research.
With the model system as the common denominator, our aim is to develop a platform where preclinical (meta)data from different resources will be captured, stored and shared in a FAIR compliant way. The goal is to improve collaborations between facilities, address specific questions in preclinical research and boost translational cancer research.
Breast cancer mouse model, mammary gland - Emilia Pulver (NKI)
Contact MCCA
For all general inquiries about MCCA, our facilities and services or how we can help with your research to combat cancer and aging, please contact Els Hermans or Jos Jonkers.
